4-Aminomethyltetrahydropyran → HCID 63711383, compound

HRID 1817908Notes

Reaction equation

HRID 1817908 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5](Cl)=[N:6][CH:7]=1.[NH2:12][CH2:13][CH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>C(N(CC)CC)C>[Br:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5]([NH:12][CH2:13][CH:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[N:6][CH:7]=1

Participants

4

Reactant 2

HCID 27732104-AminomethyltetrahydropyranHCID 70194125-Bromo-2-chloro-3-nitropyridine

Product 1

HCID 63711383HCID 63711383, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared according to the procedure described in Step A of Example 5 from 5-bromo-2-chloro-3-nitropyridine (Step B), 4-aminomethyltetrahydropyran (Apollo Scientific Ltd.) and triethylamine.

Sources & evidence

ORD record
ord-5ca3745145434bd8b7703a9c3ed4c3ee
Source dataset
uspto-grants-2009_10
Patent number
US07598393B2

Reaction notes

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