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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1817917Generated: November 2, 2026

Diisopropylethylamine → 4-(Ethylsulfonyl)-2-nitro-N-(tetrahydro-2H-pyran-2-ylmethyl)aniline

https://huagongshe.com/reaction/1817917

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant(Tetrahydro-2H-pyran-2-ylmethyl)amineHCID 97924—
Reactant1-Chloro-4-(ethylsulfonyl)-2-nitrobenzeneHCID 1515859—
Product4-(Ethylsulfonyl)-2-nitro-N-(tetrahydro-2H-pyran-2-ylmethyl)anilineHCID 68870990—

Reaction Steps

The title compound was prepared according to the procedure described in Step A of Example 5 from 1-chloro-4-(ethylsulfonyl)-2-nitrobenzene (step C of Example 2), 2-aminomethyltetrahydropyran (Sciences Chimiques 1972, 3, 685-688) and N,N-diisopropylethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598393B2
Source datasetuspto-grants-2009_10
ORD IDord-b3c237a170e84b028c39850f3825a33a
Source noteuspto-grants-2009_10