HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66917789, compound → HCID 66917764, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66917789 | HCID 66917789 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66917764 | HCID 66917764 | — |
Reaction Steps
7-Benzyloxy-2-methyl-1-naphthalen-2-ylmethyl-1H-benzoimidazole (211 mg) in methanol (12 mL) and acetic acid (1.0 mL) was hydrogenated in presence of 10% Pd—C at 45 psi for 20 h. Reaction mixture was filtered through a pad of celite. The filtrate was concentrated to afford 2-methyl-3-naphthalen-2-ylmethyl-1H-benzoimidazol-4-ol, I-111 (211 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598397B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-612407150c004baaa946f753ae10cd97 |
| Source note | uspto-grants-2009_10 |