HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Fluoro-1-benzosuberone → HCID 22391779, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Fluoro-1-benzosuberone | HCID 579050 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 22391779 | HCID 22391779 | — |
Reaction Steps
3-Fluoro-6,7,8,9-tetrahydro-benzocyclohepten-5-one (5.00 g, 28.00 mmol), NaBH3CN (12.50 g, 0.20 mol) and NH4OAc (65.00 g, 0.84 mol) in isopropanol were reacted according to the protocols as outlined in general procedure C to afford the title amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598417B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-86085947ba6d4e45ac1f151fab51f8f4 |
| Source note | uspto-grants-2009_10 |