HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → (E,E)-2-(Benzylaminocarbonyl)-3-(4-hydroxy-3-methoxystyryl)acrylonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- | HCID 9984 | — |
| Reactant | N-(cyanoacetyl)benzylamide | HCID 178511179 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (E,E)-2-(Benzylaminocarbonyl)-3-(4-hydroxy-3-methoxystyryl)acrylonitrile | HCID 11522842 | — |
Reaction Steps
The compound was prepared as described in Example 37 by adding piperidine to a solution of 4-hydroxy-3-methoxycinnamaldehyde (35 mg, 0.2 mmol) and N-(cyanoacetyl)benzylamide (34 mg, 0.2 mmol) in ethanol. After recrystallization from ethanol-water a yellow solid was obtained (50 mg, 75%). The product gave the following analytical data:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598419B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-1076ebe740ce40c7a1d72d72c5535048 |
| Source note | uspto-grants-2009_10 |