Dimethylformamide → Tert-butyl 4-(6-chloropyrazin-2-ylamino)piperidine-1-carboxylate
Reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[Cl:1][c:2]1[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1.[Cs+:27].[Cs+:28].[NH2:9][CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]1.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[c:2]1([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[n:3][c:4]([Cl:8])[cH:5][n:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-5a2a30442e9e4cf58f1945a9b5fb326b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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