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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1818919Generated: November 1, 2026

HCID 68422863, compound → HCID 68425439, compound

https://huagongshe.com/reaction/1818919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68422863HCID 68422863—
CatalystPalladiumHCID 23938—
SolventMethanol--water (1/1)HCID 22242641—
ProductHCID 68425439HCID 68425439—

Reaction Steps

Compound 7.3 (1.0 mmol) and Pd/C (10 w/w %, 60 mg) in MeOH—H2O (12 mL) is stirred under a hydrogen atmosphere at room temperature until the reaction is complete. The catalyst is removed by filtration and the filtrate is evaporated to dryness under reduced pressure to provide thieno[3,2-d]pyrimidine-4-carboxylic acid 4-amino-benzylamide (compound 7.4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07601725B2
Source datasetuspto-grants-2009_10
ORD IDord-4dd7e502aae74e529d34d5d8e4d3798e
Source noteuspto-grants-2009_10