HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18452906, compound → 2-Mercaptobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18452906 | HCID 18452906 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Potassium Carbonate | HCID 11430 | — |
| Product | 2-Mercaptobenzonitrile | HCID 11018926 | — |
Reaction Steps
Following the procedures for Example 22, Step C, decahydroisoquinoline mesylate from preparation 3 (102 mg, 0.28 mmol) in acetone (0.5 mL), potassium carbonate solid (38 mg, 0.28 mmol, twice) and 2-mercaptobenzonitrile (38 mg, 0.286 mmol, twice) gave, after flash chromatography (hexanes-ethyl acetate 2:1), the desired product as an oil (64 mg) in 57% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601738B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-d17ec1bf9a594fe49a0597fe2c5558df |
| Source note | uspto-grants-2009_10 |