HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57566815, compound → 1-(3-Aminophenyl)-4-(3-benzyloxy-4-methoxyphenyl)-pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57566815 | HCID 57566815 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol ethylacetate | HCID 21584252 | — |
| Product | 1-(3-Aminophenyl)-4-(3-benzyloxy-4-methoxyphenyl)-pyrrolidin-2-one | HCID 9977574 | — |
Reaction Steps
To a solution of 4-(3-benzyloxy-4-methoxyphenyl)-1-(3-nitrophenyl)-pyrrolidin-2-one (100 mg) in EtOAc/EtOH (2 mL, 1:1) was added Raney Ni. The mixture was then put under vacuum and recharged with H2. The mixture was stirred under H2 for 10 h. After filtration, concentration gave crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601742B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a54e3dc4c3a44f6094ba24923ff67fb8 |
| Source note | uspto-grants-2009_10 |