HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68828336, compound → HCID 68828392, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68828336 | HCID 68828336 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68828392 | HCID 68828392 | 85.1% |
Reaction Steps
3-[4-(2-Benzyloxy-4-methoxyphenyl)-2-oxo-pyrrolidin-1-yl]benzamide (1.8 g, crude) was dissolved in 50 mL of EtOH and 20 mL of EtOAc. 10% Pd/C (200 mg) was added and the mixture was stirred under H2 for 20 h. After filtration and concentration, the residue was purified on silica gel to give 1.2 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601742B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-52043c408697406984c36413a3518054 |
| Source note | uspto-grants-2009_10 |