反应详情

The above (4-{[2-(cyclohexylmethylamino)-5-nitro-pyrimidin-4-ylamino]-methyl}-cyclohexyl)-carbamic acid tert-butyl ester (32 mg, 0.07 mmol) was dissolved in dioxane (0.6 mL) and treated with 4M HCl in dioxane (0.25 mL). The reaction mixture was concentrated in vacuo and the resulting residue was purified by silica gel preparative TLC to afford 9 mg (35%) of the title compound, m/z 363.4 [M+1]+.

1. concentrationThe reaction mixture was concentrated in vacuo
2. customthe resulting residue was purified by silica gel preparative TLC