HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-2-methylindole-3-acetic acid → HCID 178488074, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-2-methylindole-3-acetic acid | HCID 76151 | — |
| Reactant | N-(4-(aminomethyl)-2,6-dichlorophenyl)acetamide | HCID 58962993 | — |
| Reactant | HCID 178488081 | HCID 178488081 | — |
| Product | HCID 178488074 | HCID 178488074 | — |
Reaction Steps
In a manner similar to that used in the preparation of the compound of example 2, but using 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetic acid in step 10 (A) and 4-acetamido-3,5-dichloro-benzylamine (preparation B) in step 10 (B), the title compound was prepared. MS (ESI) (M+H)+=476.05 1H-NMR (300 MHz, CD3OD) δ 7.42 (s, 2 H), 7.18 (d, J=8.42 Hz, 1 H), 6.96 (d, J=2.56 Hz, 1 H), 6.64-6.84 (m, J=2.56 Hz, 1 H), 4.48 (s, 2 H), 3.88 (s, 2 H), 3.80 (s, 3 H), 2.40 (s, 3 H), 2.19 (s, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601751B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-9c643a78b2e64340a3082128913b70c7 |
| Source note | uspto-grants-2009_10 |