(7-fluoro-2-methyl-1H-indol-3-yl)acetic acid → n-(2,6-Dichloro-4-{n'-[2-(7-fluoro-2-methyl-1h-indol-3-yl)-acetyl]-guanidinomethyl}-phenyl)-acetamide

Participants

Reaction Steps

In a manner similar to that used in the preparation of the compound of example 1, but using 2-(7-fluoro-2-methyl-1H-indol-3-yl)acetic acid in step 22 (A), the title compound was prepared. MS (ESI) (M+H)+=464.00 1H-NMR(500 MHz, CD3OD) δ 7.44 (s, 2 H), 7.24 (d, J=7.93 Hz, 1 H), 6.90-7.01 (m, 1 H), 6.72-6.89 (m, 1 H), 4.52 (s, 2 H), 3.93 (s, 2 H), 2.45 (s, 3 H), 2.19 (s, 3 H).

Provenance & Evidence