HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18511494, compound → HCID 18511541, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18511494 | HCID 18511494 | — |
| Reactant | 4-Chloro-1,3-benzothiazol-2-amine--hydrogen chloride (1/1) | HCID 18511603 | — |
| Product | HCID 18511541 | HCID 18511541 | — |
Reaction Steps
5-Chloro-2-(3-chloro-5-nitro-benzyl)-benzothiazole (329) was synthesized (92%) from (3-chloro-5-nitro-phenyl)-acetic acid (328, 430 mg, 2.0 mmol) and 2-amino-4-chloro-benzothiazole hydrochloride (6, 392 mg, 2.0 mmol) in a similar manner as described in Example 8. 1H NMR (400 MHz, DMSO-d6) δ 8.30 (br s, 1H), 8.22 (t, J=2.0 Hz, 1H), 8.10 (d, J=8.6 Hz, 1H), 8.06 (d, J=2.0 Hz, 1H), 8.03 (br s, 1H), 7.47 (dd, J=8.6, 2.0 Hz, 1H), 4.72 (s, 2H). MS (EI): m/z 339 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601841B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-4a4a89bad8ce46e88603ca783a3de321 |
| Source note | uspto-grants-2009_10 |