Benzoyl chloride → HCID 24899703, compound

HRID 1819865Notes

Reaction equation

HRID 1819865 reaction equation
[CH2:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[O:6][C:5]=2[CH2:4][CH2:3][CH:2]1[NH2:14].[C:15](Cl)(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>N1C=CC=CC=1>[CH:1]1[C:9]2[C:8]3[CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[O:6][C:5]=2[CH:4]=[CH:3][C:2]=1[NH:14][C:15](=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 21221605HCID 21221605, compound

Product 1

HCID 24899703HCID 24899703, compoundYield 51.5%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Following the procedure of Example 1, tetrahydro-dibenzofuran-2-ylamine (0.94 g, 5.0 mmol) and benzoyl chloride (0.64 mL, 5.5 mmol) in pyridine (10 mL) provided N-(6,7,8,9-tetrahydro-dibenzofuran-2-yl)-benzamide (0.75 g). Mp 178-180° C.; Anal. Calcd. for C19H17NO2: C, 78.33; H, 5.88; N, 4.81; Found: C, 78.10; H, 5.86; N, 4.81.

Sources & evidence

ORD record
ord-ac2a5d07e78f40788d857dae03b97cd0
Source dataset
uspto-grants-2009_10
Patent number
US07601856B2

Reaction notes

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