Hexanoyl chloride → HCID 24899706, compound

HRID 1819869Notes

Reaction equation

HRID 1819869 reaction equation
[CH2:1]1[C:9]2[C:8]3[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=3[O:6][C:5]=2[CH2:4][CH2:3][CH:2]1[NH2:14].[C:15](Cl)(=[O:21])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>ClC(Cl)C>[CH:1]1[C:9]2[C:8]3[CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[O:6][C:5]=2[CH:4]=[CH:3][C:2]=1[NH:14][C:15](=[O:21])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 67340Hexanoyl chlorideHCID 21221605HCID 21221605, compound

Product 1

HCID 24899706HCID 24899706, compoundYield 43.8%

Reagents, catalysts & solvents 1

HCID 63651,1-DichloroethaneSolvent

Procedure

Following the procedure of Example 23, tetrahydro-dibenzofuran-2-ylamine (0.15 g, 0.80 mmol), hexanoyl chloride (0.11 mL, 0.80 mmol), and poly(vinylpyridine) (0.5 g) in dichloroethane (8 mL) provided N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)hexanamide (0.10 g). MS (ESI) m/z286.

Sources & evidence

ORD record
ord-d0f4cc2ab53d4023bd9fb50a0469f517
Source dataset
uspto-grants-2009_10
Patent number
US07601856B2

Reaction notes

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