Cyclohexylacetyl chloride → HCID 24897430, compound

Participants

Reaction Steps

Following the procedure of Example 1, 6,7,8,9,10,11-Hexahydro-benzo[b]-cycloocta[d]furan-2-ylamine (1.1 g, 5.0 mmol) and cyclohexylacetyl chloride (0.88 g, 5.5 mmol) in pyridine (10 mL) provided 2-cyclohexyl-N-[6,7,8,9,10,11-hexahydro-benzo[b]-cycloocta[d]furan-2-yl]acetamide (1.3 g). Mp 180-181° C.;MS (El) m/z 340 ([M+H]+); Anal. Calcd. for C22H29NO2: C, 77.84; H, 8.61; N, 4.13; Found: C, 77.96; H, 8.70; N, 4.16.

Provenance & Evidence