HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23090907, compound → 4-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23090907 | HCID 23090907 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(Pyrrolidin-1-ylmethyl)benzoic acid hydrochloride | HCID 56773878 | 58.1% |
Reaction Steps
A solution of methyl 4-(1-pyrrolidinylmethyl)benzoate hydrochloride (3.18 g, 12.4 mmol) in 6N hydrochloric acid (30 ml) was stirred at 100° C. for 16 hrs. The solvent was evaporated under reduced pressure, and the residue was powderized with tetrahydrofuran to give the title compound (1.74 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601868B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-968b650847b048f3af8215fb47860b7a |
| Source note | uspto-grants-2009_10 |