HCID 23090907, compound → 193968-71-7

HRID 1820000Notes

Reaction equation

HRID 1820000 reaction equation
[ClH:1].[N:2]1([CH2:7][C:8]2[CH:17]=[CH:16][C:11]([C:12]([O:14]C)=[O:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3]1>Cl>[ClH:1].[N:2]1([CH2:7][C:8]2[CH:17]=[CH:16][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)[CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 1

HCID 23090907HCID 23090907, compound

Product 1

HCID 56773878193968-71-7Yield 58.1%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of methyl 4-(1-pyrrolidinylmethyl)benzoate hydrochloride (3.18 g, 12.4 mmol) in 6N hydrochloric acid (30 ml) was stirred at 100° C. for 16 hrs. The solvent was evaporated under reduced pressure, and the residue was powderized with tetrahydrofuran to give the title compound (1.74 g).

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-968b650847b048f3af8215fb47860b7a
Source dataset
uspto-grants-2009_10
Patent number
US07601868B2

Reaction notes

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