Benzoic Acid → HCID 57889679, compound

HRID 1820196Notes

Reaction equation

HRID 1820196 reaction equation
Cl.[NH2:2][C@H:3]([CH:22]([CH3:24])[CH3:23])[C:4]([N:6]1[CH2:11][CH2:10][C@@:9]([C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)([OH:12])[C:8]([CH3:21])([CH3:20])[CH2:7]1)=[O:5].[C:25](O)(=[O:32])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[Cl:19][C:16]1[CH:15]=[CH:14][C:13]([C@@:9]2([OH:12])[CH2:10][CH2:11][N:6]([C:4](=[O:5])[C@H:3]([NH:2][C:25](=[O:32])[C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[CH:22]([CH3:24])[CH3:23])[CH2:7][C:8]2([CH3:20])[CH3:21])=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 243Benzoic AcidHCID 67299922HCID 67299922, compound

Product 1

HCID 57889679HCID 57889679, compound

Procedure

Example 327 was prepared in a similar manner as described in Example 75 from (R)-2-amino-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methylbutan-1-one hydrochloride and benzoic acid.

Workup

  1. customExample 327 was prepared in a similar manner

Sources & evidence

ORD record
ord-7a8af0d74c0e4ee381c43f96649908c1
Source dataset
uspto-grants-2009_10
Patent number
US07601844B2

Reaction notes

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