HuagongsheHuagongshe Chemistry Print Report · For research reference only
Octahydropyrrolo(1,2-a)pyrazine → HCID 68682026, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Octahydropyrrolo(1,2-a)pyrazine | HCID 558578 | — |
| Reactant | 2-(Morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acid | HCID 68681581 | — |
| Product | HCID 68682026 | HCID 68682026 | 65% |
Reaction Steps
The title compound was synthesized in analogy to example 46, intermediate e), from 2-(morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acid and 1,4-diazabicyclo[4.3.0]nonane (purchased at Matrix Ref 8078), to give the desired product as a white solid (65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601711B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-181144088882444fb494b7753f86ac52 |
| Source note | uspto-grants-2009_10 |