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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820557Generated: November 2, 2026

1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → HCID 68681774, compound

https://huagongshe.com/reaction/1820557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
Reactant4,4-Difluoropiperidine hydrochlorideHCID 2758351—
ReactantHCID 68682285HCID 68682285—
SolventTriethylamineHCID 8471—
ProductHCID 68681774HCID 68681774—

Reaction Steps

The title compound was synthesized in analogy to Example 1, from 5-(3-dimethylamino-piperidine-1-carbonyl)-1-isopropyl-1H-indole-2-carboxylic acid, 4,4-difluoropiperidine hydrochloride, triethylamine and 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride, to afford the product as a light-brown oil (79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07601711B2
Source datasetuspto-grants-2009_10
ORD IDord-fce9b5b43e8149c89e06a1660e26b953
Source noteuspto-grants-2009_10