1-(4-Chlorophenyl)piperazine → HCID 87644809, compound

HRID 1820688Notes

Reaction equation

HRID 1820688 reaction equation
[C:1]([CH2:3][N:4]([C:16]1[CH:21]=[CH:20][N:19]=[C:18](F)[N:17]=1)[C:5](=[O:15])[C@H:6]([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[NH2:7])#[N:2].[Cl:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)=[CH:26][CH:25]=1>>[Cl:23][C:24]1[CH:25]=[CH:26][C:27]([N:30]2[CH2:35][CH2:34][N:33]([C:18]3[N:17]=[C:16]([N:4]([CH2:3][C:1]#[N:2])[C:5](=[O:15])[C@H:6]([CH2:8][C:9]4[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=4)[NH2:7])[CH:21]=[CH:20][N:19]=3)[CH2:32][CH2:31]2)=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 974781-(4-Chlorophenyl)piperazineHCID 87644431HCID 87644431, compound

Product 1

HCID 87644809HCID 87644809, compound

Procedure

The title compound was prepared from the product of example 5 step (ii) (0.2 g) and 4(4-chlorophenyl)piperazine by the method of example 1 step (iv). Yield 0.18 g.

Sources & evidence

ORD record
ord-cc36c104da844ea8836d81c9ac4eba6f
Source dataset
uspto-grants-2009_10
Patent number
US07605159B2

Reaction notes

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