1-(4-Chlorophenyl)piperazine → HCID 87969794, compound

HRID 1820689Notes

Reaction equation

HRID 1820689 reaction equation
[C:1]([CH2:3][NH:4][C:5](=[O:22])[C@H:6]([CH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[NH:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10](F)[N:9]=1)#[N:2].[Cl:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)=[CH:26][CH:25]=1>>[Cl:23][C:24]1[CH:25]=[CH:26][C:27]([N:30]2[CH2:35][CH2:34][N:33]([C:10]3[N:9]=[C:8]([NH:7][C@H:6]([C:5]([NH:4][CH2:3][C:1]#[N:2])=[O:22])[CH2:15][CH:16]4[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]4)[CH:13]=[CH:12][N:11]=3)[CH2:32][CH2:31]2)=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 974781-(4-Chlorophenyl)piperazineHCID 131727667HCID 131727667, compound

Product 1

HCID 87969794HCID 87969794, compound

Procedure

The title compound was prepared from the product of example 8 step (ii) (0.2 g) and 4(4-chlorophenyl)piperazine (0.66 g) by the method of example 1 step (iv). Yield 0.2 g.

Sources & evidence

ORD record
ord-f44c7208c2c048129a63946e2e613633
Source dataset
uspto-grants-2009_10
Patent number
US07605159B2

Reaction notes

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