Hydrochloric Acid → 1-(4-Oxazol-2-yl-phenyl)-piperazine hydrochloride

HRID 1820741Notes

Reaction equation

HRID 1820741 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[O:21][CH:22]=[CH:23][N:24]=3)=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25]>O1CCOCC1>[ClH:25].[O:21]1[CH:22]=[CH:23][N:24]=[C:20]1[C:17]1[CH:16]=[CH:15][C:14]([N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 690421064-(4-Oxazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 690424061-(4-Oxazol-2-yl-phenyl)-piperazine hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Prepared in analogy to example 4.4(b) from 4-(4-Oxazol-2-yl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester and hydrochloric acid in dioxane. MS (m/e): 230.1 (MH+, 100%)

Sources & evidence

ORD record
ord-800a003a99a749ac85c472a2879dae21
Source dataset
uspto-grants-2009_10
Patent number
US07605163B2

Reaction notes

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