HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-Methoxy-6-(piperazin-1-yl)pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 6'-Methoxy-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid tert-butyl ester | HCID 69041341 | — |
| Product | 2-Methoxy-6-(piperazin-1-yl)pyrazine | HCID 13318698 | — |
Reaction Steps
Prepared in analogy to example 4.10(c) from 6′-Methoxy-2,3,5,6-tetrahydro-[1,2′]bipyrazinyl-4-carboxylic acid tert-butyl ester and trifluoroacetic acid. MS (m/e): 195.1 (MH+, 80%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605163B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-6200a4eaf50c48b5a8c666f95d43d726 |
| Source note | uspto-grants-2009_10 |