Alumina → HCID 57892086, compound

HRID 1820868Notes

Reaction equation

HRID 1820868 reaction equation
[N+:1]([C:4]1[CH:18]=[CH:17][C:7]2[N:8]=[C:9]([CH2:11][N:12]3[CH2:16][CH2:15][CH2:14][CH2:13]3)[O:10][C:6]=2[CH:5]=1)([O-])=O.[O-2].[Al+3].[O-2].[O-2].[Al+3].ClCCl.C(O)C>CO>[N:12]1([CH2:11][C:9]2[O:10][C:6]3[CH:5]=[C:4]([NH2:1])[CH:18]=[CH:17][C:7]=3[N:8]=2)[CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

5

Reactant 3

HCID 9989226AluminaHCID 21584144Dichloromethane ethanolHCID 68980202HCID 68980202, compound

Product 1

HCID 57892086HCID 57892086, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogously to Example VI.1.d from 1.80 g (7.28 mmol) of 6-nitro-2-(pyrrolidin-1-ylmethyl)benzoxazole (VIII.1.b) in methanol as solvent. Yield: 1.10 g (70% of theory); Rf value: 0.60 (aluminum oxide, dichloromethane/ethanol=20:1); C12H15N3O; EII mass spectrum: m/z=218 [M+H]+.

Sources & evidence

ORD record
ord-1aa625a669d046d1a2306bdcd6f15e27
Source dataset
uspto-grants-2009_10
Patent number
US07605176B2

Reaction notes

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