Dimethylamine → HCID 58979991, compound

HRID 1821189Notes

Reaction equation

HRID 1821189 reaction equation
[NH:1]1[C:5]2=[N:6][CH:7]=[CH:8][C:9]([C:10]3[S:11][CH:12]=[CH:13][C:14]=3[C:15]3[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=3)=[C:4]2[CH:3]=[CH:2]1.[CH3:22][NH:23][CH3:24].[O:25]1[CH2:29]CCC1>>[CH3:22][N:23]([CH3:24])[C:29]([NH:19][C:18]1[CH:20]=[CH:21][C:15]([C:14]2[CH:13]=[CH:12][S:11][C:10]=2[C:9]2[CH:8]=[CH:7][N:6]=[C:5]3[NH:1][CH:2]=[CH:3][C:4]=23)=[CH:16][CH:17]=1)=[O:25]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 8028TetrahydrofuranHCID 69003971HCID 69003971, compound

Product 1

HCID 58979991HCID 58979991, compound

Procedure

Following the procedure described in Example 5a with 4-[2-(1H-pyrrolo[2,3-b]pyridin-4-yl)-3-thienyl]aniline and 2M dimethylamine in tetrahydrofuran provided title compound. ESMS [M+H]+: 363.2

Sources & evidence

ORD record
ord-6931315deb004af08086550c1129925e
Source dataset
uspto-grants-2009_10
Patent number
US07605266B2

Reaction notes

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