HRID1821213

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31268

Pyrrolidine

C4H9N

结构：CN(C)C(=O)Nc1ccc(-c2nn(C)cc2-c2ccnc3[nH]c(-c4ccc(C=O)cc4)cc23)cc1

HCID86613318

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)Nc1ccc(-c2nn(C)cc2-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)cc1

HCID24816132

未命名化合物

PROCEDURE

实验过程

Following the procedure described for Intermediate 101 using N′-(4-{4-[2-(4-formylphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1H-pyrazol-3-yl}phenyl)-N,N-dimethylurea and pyrrolidine provided the title compound. ESMS [M+H]+: 520.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8ca87641bc004e1097466284a856dd26
来源数据集: uspto-grants-2009_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07605266B2
来源说明: uspto-grants-2009_10

反应 SMILES

[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[NH:35][C:12]3=[N:13][CH:14]=[CH:15][C:16]([C:17]4[C:18]([C:23]5[CH:28]=[CH:27][C:26]([NH:29][C:30](=[O:34])[N:31]([CH3:33])[CH3:32])=[CH:25][CH:24]=5)=[N:19][N:20]([CH3:22])[CH:21]=4)=[C:11]3[CH:10]=2)=[CH:5][CH:4]=1)=O.[NH:36]1[CH2:40][CH2:39][CH2:38][CH2:37]1>>[CH3:32][N:31]([CH3:33])[C:30]([NH:29][C:26]1[CH:27]=[CH:28][C:23]([C:18]2[C:17]([C:16]3[CH:15]=[CH:14][N:13]=[C:12]4[NH:35][C:9]([C:6]5[CH:5]=[CH:4][C:3]([CH2:1][N:36]6[CH2:40][CH2:39][CH2:38][CH2:37]6)=[CH:8][CH:7]=5)=[CH:10][C:11]=34)=[CH:21][N:20]([CH3:22])[N:19]=2)=[CH:24][CH:25]=1)=[O:34]