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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1821329Generated: October 31, 2026

Trifluoroacetic acid → HCID 68997636, compound

https://huagongshe.com/reaction/1821329

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 69002669HCID 69002669—
SolventDichloromethaneHCID 6344—
ProductHCID 68997636HCID 6899763696%

Reaction Steps

(E)-(5-{2-[2-(1H-indazol-3-yl)vinyl]phenylcarbamoyl}-1-methyl-1H-pyrrol-3-yl) carbamic acid tert-butyl ester (15 mg, 0.033 mmol) was dissolved in methylene chloride (1.0 mL) and trifluoroacetic acid (100 μL) was added thereto followed by stirring at room temperature for 5 hours. Then, the mixture was concentrated and dried to obtain Compound 76 (11.3 mg, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605272B2
Source datasetuspto-grants-2009_10
ORD IDord-47710a98737b4d3484bb2e4c7b81a288
Source noteuspto-grants-2009_10