反应详情

(1H-Indazol-3-ylmethyl)triphenylphosphonium bromide (0.64 g, 1.3 mmol) was dissolved in methanol (8.0 mL) and the solution was added with 4-(morpholin-4-yl)-2-nitrobenzaldehyde (0.35 g, 1.5 mmol) and potassium carbonate (0.37 g, 2.7 mmol), followed by stirring at room temperature for 1 hour. The reaction mixture was added with water and the precipitated solid was collected by filtration and dried. The obtained solid was triturated in methanol to obtain (E)-3-([2-[4-(morpholin-4-yl)-2-nitrophenyl]vinyl]-1H-indazole (0.41 g, 86%).

1. filtrationthe precipitated solid was collected by filtration
2. customdried
3. customThe obtained solid was triturated in methanol