反应详情

Cyclic anhydride 42 (405 mg; 1.73 mmol) was dissolved in aqueous NH4OH and heated at reflux for 1.5 h. The mixture was cooled to RT and the solid was filtered then dried overnight to give 270 mg (74%) of the title compound.

1. temperatureheated
2. temperatureat reflux for 1.5 h
3. filtrationthe solid was filtered
4. customthen dried overnight