4-Methylpiperidine → (6-Hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanone

HRID 1821609Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([OH:14])=O)[CH:6]=[CH:5]2.[CH3:15][CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]([N:19]1[CH2:20][CH2:21][CH:16]([CH3:15])[CH2:17][CH2:18]1)=[O:14])[CH:6]=[CH:5]2

Participants

Reactant 2

HCID 693814-Methylpiperidine

HCID 855576-Hydroxy-2-naphthoic acid

Product 1

HCID 58933892(6-Hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanone

Procedure

The title compound was synthesised from 6-hydroxy-2-naphtoic acid (commercially available) and 4-methyl-piperidine (commercially available) according to the procedure described for Example A. MS (m/e): 268.5 (MH−, 100%)

Sources & evidence

ORD record: ord-87beb45a12fe40feab976244cd7a1edc
Source dataset: uspto-grants-2009_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07608617B2

Reaction notes

Loading…