HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-3-(piperidin-1-yl)propan-1-ol → [6-(2,2-Dimethyl-3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-(4-methyl-piperidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-3-(piperidin-1-yl)propan-1-ol | HCID 296014 | — |
| Reactant | (6-Hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanone | HCID 58933892 | — |
| Product | [6-(2,2-Dimethyl-3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-(4-methyl-piperidin-1-yl)-methanone | HCID 69062749 | — |
Reaction Steps
The title compound was synthesised from (6-hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanone (intermediate B) and 2,2-dimethyl-3-piperidin-1-yl-propan-1-ol (commercially available) according to the procedure described for the synthesis of Example 1. MS (m/e): 423.1 (MH+, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608617B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-e854fd8b90cd4d0cab66a561a98fef51 |
| Source note | uspto-grants-2009_10 |