反应详情

A solution of [2-(1-Ethyl-1,2,3,4-tetrahydro-quinolin-3-ylmethoxy)-5-methyl-phenyl]-carbamic acid tert-butyl ester (40 mg, 0.1 mmol) was stirred in 4N HCl in dioxane (2 mL) at room temperature under a drying tube overnight. The suspension was concentrated by rotovap, diluted to 30 mL with CH2Cl2 and shaken with 10% Na2CO3 (30 mL). The organics were isolated, dried (MgSO4), filtered and concentrated to a brown oil, which was used without purification in the following reaction.

1. concentrationThe suspension was concentrated by rotovap
2. additiondiluted to 30 mL with CH2Cl2
3. customThe organics were isolated
4. dry with materialdried (MgSO4)
5. filtrationfiltered
6. concentrationconcentrated to a brown oil, which
7. customwas used without purification in the following reaction