HCID 57893495, compound → HCID 57893529, compound

Participants

Reaction Steps

2-(1-Pyrrolidinylcarbonyl)-1H-pyrrolo[2,3-c]pyridine (22 mg, 46%) was prepared as an off-white solid following the procedure described for Example 27 using 7-chloro-2-(1-pyrrolidinylcarbonyl)-1H-pyrrolo[2,3-c]pyridine (Example 13) and ethanol as a solvent: mp 260-275° C. dec.; 1H NMR (300 MHz, CD3OD) δ1.98-2.10 (4H, m), 3.66-3.71 (2H, m), 3.89-3.94 (2H, m), 7.10 (1H, s), 7.74 (1H, d, J=5.4 Hz), 8.13 (1H, d, J=5.7 Hz), 8.82 (1H, s); ESI MS m/z 216 [C12H13N3O+H]+; HPLC (Method A) 93.3% (AUC), tR=10.3 min.

Provenance & Evidence