反应详情

0.045 g (0.105 mmol) tert-butyl-1-[3-(4-octylphenoxy)-2-oxopropyl]pyrrole-2-carboxylate is dissolved in 10 ml absolute dichloromethane and mixed with 0.900 g (7.89 mmol) trifluoroacetic acid. After stirring at room temperature for 1 hour, the batch is concentrated to dryness on the rotary evaporator. Two dissolutions in toluene and respective concentration on the rotary evaporator leave as a crude product a brownish solid which is recrystallized from methanol and some water drops and yields the product as a beige solid.

1. concentrationthe batch is concentrated to dryness on the rotary evaporator
2. concentrationTwo dissolutions in toluene and respective concentration
3. customon the rotary evaporator
4. customleave as a crude product a brownish solid which
5. customis recrystallized from methanol