Iodoethane → HCID 10256039, compound

Participants

Reaction Steps

100 mg of 5-(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-2H-tetrazole, 48 mg of ethyl iodide and 141 mg of potassium carbonate are stirred for 4 hours at 50° C. in 3 ml of dimethylformamide. The reaction mixture is poured onto water and extracted with ethyl acetate. Concentration of the organic phase and purification over silica gel yield 5-(4-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propoxy}-phenyl)-2-ethyl-2H-tetrazole (compound 1.4).

Provenance & Evidence