HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-(Pyridin-3-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-(3-Pyridinyl)-2-propenoic acid | HCID 101984 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(Pyridin-3-yl)propanoic acid | HCID 259624 | 100.7% |
Reaction Steps
A mixture of 3-(pyridin-3-yl)propenoic acid (10.0 g, 67 mmol), 10% palladium-activated carbon (1 g), methanol (100 mL) and ethanol (100 mL) was stirred overnight under hydrogen atmosphere. The resultant reaction mixture was filtered, evaporated, and dried to give 3-(pyridin-3-yl)propionic acid (10.2 g, quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608716B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-3adadc5cf5c848bdbcdd801caaaac1cc |
| Source note | uspto-grants-2009_10 |