HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-phenoxyphenol → 3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-phenoxyphenol | HCID 12774295 | — |
| Reactant | 3-[4-(3-Bromo-5-methyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester | HCID 57894212 | — |
| Product | 3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid | HCID 11477347 | — |
Reaction Steps
The title compound is prepared by reacting the compound of 3-[4-(3-bromo-5-methyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester with 4-chloro-2-phenoxy-phenol as in Example 18 to afford 0.118 g (22%). 1H NMR (400 MHz, CDCl3); HRMS (ES+) m/z exact mass calculated for C29H25O5Cl 489.1469, found 489.1457.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608639B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-40bab35ad24b46738bee039341dd474f |
| Source note | uspto-grants-2009_10 |