HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetylphenylboronic acid → 3-{4-[3-(2'-Acetyl-5-trifluoromethyl-biphenyl-2-yloxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetylphenylboronic acid | HCID 2734309 | — |
| Reactant | HCID 57894173 | HCID 57894173 | — |
| Product | 3-{4-[3-(2'-Acetyl-5-trifluoromethyl-biphenyl-2-yloxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid | HCID 11330263 | — |
Reaction Steps
The title compound is prepared by reacting the compound of 3-{4-[3-(2-bromo-4-trifluoromethyl-phenoxy)-5-methyl-phenoxy]-2-methyl-phenyl}-propionic acid ethyl ester with 2-acetyl phenyl boronic acid as in Example 38 to afford 0.032 g (28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608639B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-d52afd48acd34d2a92536e9754dea021 |
| Source note | uspto-grants-2009_10 |