HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-phenoxyphenol → 3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-5-ethyl-phenoxy]-2-methyl-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-phenoxyphenol | HCID 12774295 | — |
| Reactant | 3-[4-(3-Bromo-5-ethyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester | HCID 57894146 | — |
| Product | 3-{4-[3-(4-Chloro-2-phenoxy-phenoxy)-5-ethyl-phenoxy]-2-methyl-phenyl}-propionic acid | HCID 57894145 | 36% |
Reaction Steps
The compound of 3-[4-(3-bromo-5-ethyl-phenoxy)-2-methyl-phenyl]-propionic acid methyl ester is reacted with 4-chloro-2-phenoxy-phenol as in Example 18 to afford 0.237 g (36%) of the title compound after saponification. 1H NMR (400 MHz, CDCl3); HRMS (ES+) m/z exact mass calculated for C30H28O5Cl 503.1625, found 503.1625.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07608639B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-096e1a8f508b4890b1aa7b25eab3051b |
| Source note | uspto-grants-2009_10 |