Pinacol → 4,4,5,5-Tetramethyl-2-[3-(trifluoromethoxy)phenyl]-1,3,2-dioxaborolane

HRID 1822670Notes

Reaction equation

HRID 1822670 reaction equation
[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:5]=[C:6]([B:10]([OH:12])[OH:11])[CH:7]=[CH:8][CH:9]=1.O[C:16]([C:19](O)([CH3:21])[CH3:20])([CH3:18])[CH3:17]>>[CH3:17][C:16]1([CH3:18])[C:19]([CH3:21])([CH3:20])[O:12][B:10]([C:6]2[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:1])([F:13])[F:14])[CH:5]=2)[O:11]1

Participants

3

Reactant 2

HCID 6425PinacolHCID 27343853-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 27606024,4,5,5-Tetramethyl-2-[3-(trifluoromethoxy)phenyl]-1,3,2-dioxaborolaneYield 25%

Procedure

The title compound (25%, oil) was prepared from 3-trifluoromethoxyphenylboronic acid and pinacol.

Sources & evidence

ORD record
ord-fe21b898333c47c0a071ef2a3851cc9f
Source dataset
uspto-grants-2006_05
Patent number
US07037905B2

Reaction notes

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