Pinacol → 2-(3-Chloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HRID 1822672Notes

Reaction equation

HRID 1822672 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([B:9]([OH:11])[OH:10])[CH:5]=[CH:6][C:7]=1[F:8].O[C:13]([C:16](O)([CH3:18])[CH3:17])([CH3:15])[CH3:14]>>[Cl:1][C:2]1[CH:3]=[C:4]([B:9]2[O:10][C:16]([CH3:18])([CH3:17])[C:13]([CH3:15])([CH3:14])[O:11]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 6425PinacolHCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 100153032-(3-Chloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneYield 77%

Procedure

The title compound (77%, oil) was prepared from 3-chloro-4-fluorophenylboronic acid and pinacol.

Sources & evidence

ORD record
ord-f923e1c589de4bc7a2910ceae84dcd5c
Source dataset
uspto-grants-2006_05
Patent number
US07037905B2

Reaction notes

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