Pinacol → 4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane

HRID 1822674Notes

Reaction equation

HRID 1822674 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:4]=[C:5]([B:9]([OH:11])[OH:10])[CH:6]=[CH:7][CH:8]=1.O[C:15]([C:18](O)([CH3:20])[CH3:19])([CH3:17])[CH3:16]>>[CH3:16][C:15]1([CH3:17])[C:18]([CH3:20])([CH3:19])[O:10][B:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:12])[F:13])[CH:4]=2)[O:11]1

Participants

3

Reactant 2

HCID 6425PinacolHCID 27343883-(Trifluoromethyl)phenylboronic acid

Product 1

HCID 27606044,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolaneYield 47%

Procedure

The title compound (47%, oil) was prepared from 3-trifluoromethylphenylboronic acid and pinacol.

Sources & evidence

ORD record
ord-486506dfd85d468b9d9bc3491aaa1b22
Source dataset
uspto-grants-2006_05
Patent number
US07037905B2

Reaction notes

Loading…