HuagongsheHuagongshe Chemistry Print Report · For research reference only
Paclitaxel → Sodium Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Paclitaxel | HCID 36314 | — |
| Reactant | 5-[(2S)-2-hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol | HCID 100154 | — |
| Reactant | Sodium chloride; water | HCID 57417360 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Sodium Chloride | HCID 5234 | 0.9% |
| Product | Paclitaxel | HCID 36314 | — |
Reaction Steps
Drug administration: For administration to rodents, CA4P was dissolved in normal saline (0.9% NaCl). Paclitaxel was dissolved in a 50/50 mixture of ethanol and Cremophor® and stored at 4° C.; final dilution of paclitaxel was obtained immediately before drug administration with NaCl 0.9%. Fresh preparation of paclitaxel was employed to avoid precipitation. CPT-11 was dissolved in normal saline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037906B1 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-0ca863e88c6047fea35bbf110b6bd8d2 |
| Source note | uspto-grants-2006_05 |