HCID 14801183, compound → 39053-19-5

HRID 1822864Notes

Reaction equation

HRID 1822864 reaction equation
[CH3:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][CH:8]=[CH:7][C:3]=1[CH2:4][O:5][CH3:6]>CCOC(C)=O.CCO.[Pd]>[CH3:6][O:5][CH2:4][C:3]1[C:2]([CH3:1])=[C:10]([CH:9]=[CH:8][CH:7]=1)[NH2:11]

Participants

4

Reactant 1

HCID 14801183HCID 14801183, compound

Product 1

HCID 1480118439053-19-5Yield 78.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 21584252Ethanol ethylacetateSolvent

Procedure

A mixture of methyl 2-methyl-3-nitrobenzyl ether (0.19 g, 1.05 mmol), and 5% Pd/C (70 mg) in EtOAc/EtOH 1:1 (14 ml) was hydrogenated at 1 atm over night. The mixture was filtered through Celite, and the filtrate was concentrated to give the title compound 125 mg (78%) as a yellow oil.

Workup

  1. waitwas hydrogenated at 1 atm over night
  2. filtrationThe mixture was filtered through Celite
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-0a1c6ec283e84342b376c613275e3f38
Source dataset
uspto-grants-2006_05
Patent number
US07037925B2

Reaction notes

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