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Hydrochloric Acid → 2,5-Dimethyl-4-(2-morpholin-4-yl-ethoxy)aniline dihydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | N-{2,5-Dimethyl-4-[2-(morpholin-4-yl)ethoxy]phenyl}acetamide | HCID 22169683 | — |
| 生成物 | 2,5-Dimethyl-4-(2-morpholin-4-yl-ethoxy)aniline dihydrochloride | HCID 22169674 | — |
反応手順
The mixture of N-[2,5-dimethyl-4-(2-morpholin-4-yl-ethoxy)-phenyl]-acetamide (11.4 g, 39 mmol) in 3N aq.HCl (100 mL) was refluxed for 2 h and then concentrated under reduced pressure. The residue was lyophilized to give 2,5-dimethyl-4-(2-morpholin-4-yl-ethoxy)aniline dihydrochloride as gray solid quantitatively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07037909B2 |
| 出典データセット | uspto-grants-2006_05 |
| ORD ID | ord-81c71f63cc804866bd3cc3fc12965995 |
| 出典メモ | uspto-grants-2006_05 |