反应详情

The mixture of N-[2,5-dimethyl-4-(2-morpholin-4-yl-ethoxy)-phenyl]-acetamide (11.4 g, 39 mmol) in 3N aq.HCl (100 mL) was refluxed for 2 h and then concentrated under reduced pressure. The residue was lyophilized to give 2,5-dimethyl-4-(2-morpholin-4-yl-ethoxy)aniline dihydrochloride as gray solid quantitatively.

1. concentrationconcentrated under reduced pressure