HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 68614531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Reactant | HCID 86592632 | HCID 86592632 | — |
| Product | HCID 68614531 | HCID 68614531 | — |
Reaction Steps
In an analogous manner to that described in Example 1d), the alkylation of the (RS)-1-(4-hydroxyoxy-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester with 4-fluorobenzylbromide in presence of potassium carbonate yields the (RS)-1-[4-(4-fluoro-benzyloxy)-phenyl]-5-oxo-pyrrolidine-3-carboxylic acid methyl ester as a light yellow powder; MS: m/e=344 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07037935B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-e5adad0f2f384b56a2426414b6471292 |
| Source note | uspto-grants-2006_05 |